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Persistent Depression Damages Cognitive Functions, Study Concludes

Persistent Depression Damages Cognitive Functions, Study Concludes

A global study involving 9,000 people has found that persistent and recurring depression can lead to a shrinking of one key area of the brain. This zone is known as the hippocampus (Greek for seahorse) and it does indeed look like one.

This is the area which helps us store long term memories and plays an essential role in connecting our emotions to memories, personality, and consciousness. It can also help us with spatial navigation. It is one of the first areas of the brain to be affected by Alzheimer’s and explains why recent memories are such a big problem for those affected.

Research details

The depression research project involved 15 institutes from all over the world. Researchers compared people possessing normal hippocampi with those who were suffering from persistent depression. This was the largest comparative study of brain volumes ever carried out. The results showed that people who had no treatment for depression (or had recurring episodes over long periods) ended up with a smaller hippocampus.

Researchers used brain magnetic resonance imaging (MRI) and this clearly showed that two thirds of the depressed patients who had recurrences over long periods of time were the ones who had a smaller hippocampus.

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“The more episodes of depression a person had, the greater the reduction in hippocampus size.” – Prof. Ian Hickie, co-director of the research project

What are the implications for the treatment of depression?

First, the good news is that treatment with anti-depressants may help to preserve the size of the hippocampus. There are a wide variety of these drugs available, including Selective Serotonin Reuptake Inhibitors, or SSRIs, which help to balance serotonin and can improve mood. Other popular medications include tricyclic antidepressants.

Of course, it must be remembered that all anti-depressants are required by the FDA to carry a black box warning of possible suicidal thoughts. This usually occurs at the beginning of treatment in teens and young adults or if a drug or dosage is changed.

“There is a lot of nonsense said about antidepressants that constantly perpetuates the evils of them, but there is a good bit of evidence that they have a protective effect.”- Prof. Ian Hickie.

Experts are now convinced that medication in treating depression is just one of the many alternatives available.

Why talk therapy is a valid alternative

Talk therapy is another possible treatment for depression, with various types that can suit individual needs. The chance to talk about depression without being judged, misunderstood or even criticized cannot be overestimated. It is a great way to approach problems and possible ways of solving them. Most medications can never do that quite as effectively.

Additionally, there is a wide range of supplements and lifestyle changes which can help a patient to maintain balance and prevent relapses. These can range from exercise which helps the brain to rewire itself in positive ways to dietary and mindfulness routines.

Research presents no conclusive results regardging the use of supplements but it seems that fish oil, SAMe and folic acid hold out some promise.

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“There’s promising evidence for certain supplements for depression. But more research needs to be done before we’ll know for sure.” – Dr. Ian Cook, Director of the Depression Research Program at UCLA.

The way forward

Depression is still not fully understood. We know that certain areas of the brain such as the hippocampus are involved, but experts are not sure how they all interlink and what mechanisms are at work.

“Despite intensive research aimed at identifying brain structures linked to depression in recent decades, our understanding of what causes depression is still rudimentary.”- Prof. Jim Lagapoulos, co-author of the research project, Brain and Mind Research Institute, University of Sydney.

One thing is certain. We have learned from the research on the hippocampus that lack of treatment or recurring depression are affecting the brain. Processing emotions and memories are at risk. That sends a very clear message — there may be other areas of the brain affected which may have more serious consequences. But this damage is in many cases also reversible.

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This is why we can never ignore depression and always seek treatment when or if it should happen to us or our loved ones.

Featured photo credit: Sigh, Clouds, Rain, Sigh, Iceland via flickr.com

More by this author

Robert Locke

Author of Ziger the Tiger Stories, a health enthusiast specializing in relationships, life improvement and mental health.

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Last Updated on January 11, 2021

11 Hidden Benefits of Using Oil Diffusers

11 Hidden Benefits of Using Oil Diffusers

Affordable, relaxing, and healthy, oil diffusers are gaining popularity with people everywhere due to their extensive benefits. Oil diffusers work through the simple process of oil diffusion, which uses heat to turn oil into a vapor that is then spread around a living space. Diffused oil can have several relaxation and health-related benefits, including safe scent-dispersion, mosquito and mold defense, stress relief, and more!

Read on for 11 hidden benefits of using oil diffusers.

1. Safe Scents That Make Sense

Unlike candles or air fresheners, oil diffusers release cleansing molecules into your air that work to purify it, not overload it with unhealthy chemicals. Electronic diffusers also do not pose the fire risk that candles do. Plus, they contain the added feature of interchangeability, which means you change oil types for different scents and health benefits.

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2. Stress Relief

Several lab studies have confirmed that diffusing essential oils like lavender have been shown to reduce stress and help relieve anxiety in medical patients. Preliminary studies have also shown that oil diffusers can help alleviate symptoms of depression.

3. Improved Sleep

Diffused oil has relaxing properties that can help people of all ages fall asleep quicker and sleep more soundly. Electronic diffusers not only have the option to mix and match different oil blends (Try a lavender, Bulgarian rose, and Roman chamomile blend to help with insomnia), they also run at a gentle hum that helps relax an agitated mind. Many also come with an auto shut-off feature to help conserve oils once you have fallen asleep.

4. Appetite Control

Much like gum, oil diffusers can help stimulate the senses in a way that works to curb appetite. New research has shown that diffused peppermint oil can help curb appetite by inducing a satiety response within the body. Diffused peppermint oil has also been shown to increase energy.

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5. Bacteria and Mold Killing

When essential oils are diffused in the air, they break down free radicals that contribute to the growth of harmful bacteria. Eucalyptus, thyme, and tea tree oils are especially good for this purpose. Diffused oil is also highly effective when it comes to combating fungal yeast threats, as the oil help makes the air inhospitable for yeasts such as mold. Pine and red thyme essential oils are best for combating mold.

6. Decongestion and Mucus Control

Ever tried Vick’s Vapo-Rub? Its decongesting powers come from active ingredients made from the eucalyptus tree. In principle, oil diffusers work the same way as Vapo-Rub, except they diffuse their decongesting vapor all around the room, not just on your chest or neck. Oil diffusers have been known to cure pneumonia in lab mice.

7. Mosquito Repellant

Nobody likes mosquitoes — but when the trade-off means using repellants full of DEET, a toxic chemical that can be especially harmful to children, mosquito control can often seem like a lose-lose. However, scientists have shown that oil diffusers can be used as a safe and highly effective mosquito repellant. Studies have shown that a diffused oil mixture containing clove essential oil and lemongrass essential oil repelled one type of Zika-carrying mosquito, the Aedes aegypti mosquito, at a rate of 100%.

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8. Pain Relief

While applying oils directly to areas of your body may be the most effective way to alleviate pain, diffusing essential oils can also be an effective means of pain relief. When we inhale healthy essential oils, they enter our blood stream and can help internally relieve persistent pain from headaches, overworked muscles, and sore joints.

9. The New Anti-Viral

Research into the anti-viral effects of oil diffusion is now just gaining steam. A recent study showed that star anise essential oil was proven in medical experiments to destroy the herpes simplex virus in contained areas at a rate of 99%. Another study showed the popular DoTerra oil blend OnGuard to have highly-effective influenza-combating powers.

10. Improved Cognitive Function

Diffusing essential oils has also been shown to improve cognitive function. Many essential oils have adaptogenic qualities, which can work twofold in soothing us when we’re stressed, and giving our bodies a pick-me-up when we’re feeling down or sluggish. By working to level out an imbalanced mood, diffused oils also help us to focus. There are also several essential oils which have been shown to help balance the body’s hormones. With prolonged use, these oils can work to repair the underlying causes responsible for hindering cognitive function.

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11. Money Saving

With ten clear benefits of oil diffusers already outlined, there is one more that should now be obvious: using an oil diffuser will help you to save money. As an anti-viral, bug repelling, and stress-relief solution rolled into one safe product, an oil diffuser used with the proper oils will save you money on products you might otherwise be buying to help cure those pesky headaches or get your kids to fall asleep on time. If you’re wondering just how affordable oil diffusers can be, check the buyer’s guide to the best oil diffusers — you’ll be sure to find one that fits your budget!

Featured photo credit: Jopeel Quimpo via unsplash.com

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