Advertising
Advertising

Do Antidepressants Work For You? Brain Waves May Predict

Do Antidepressants Work For You? Brain Waves May Predict

For almost half a century, patients suffering from severe depressive and anxiety disorders have relied on antidepressants for relief. But to any depression sufferer, finding the right medication is the hardest part of drug therapy. Not every drug works the same and figuring out what prescription interacts correctly with the body can take months to years.

The study

Luckily, we’re in 2016, a year in which psychopharmacology has advanced dramatically – and this notion echoes with antidepressants. A new study published in the Semel Institute for Neuroscience and Human Behavior at UCLA aimed to predict whether or not an antidepressant would work in the long term.

According to Dr. Andrew Leuchter, the lead author of the study, researchers were able to predict the outcome of the selective serotonin reuptake inhibitor (SSRI) antidepressant drug Lexapro, using brain wave recordings. Additionally, researchers were able to analyze electroencephalogram recordings to foresee if recovery or relapse from depressive episodes were to occur.

Advertising

“Knowing whether a medication is going to work could eliminate weeks of waiting for the patient, and get them on effective treatment more quickly,” Dr. Leuchter said.

Lexapro, like other antidepressants, works by increasing the neurotransmitter serotonin, which is responsible for mood, energy, and behavior. However, serotonin is also able to stabilize slow and fast brain waves caused by a chemical reaction.

In the study, researchers gathered data from 194 clinically depressed patients, aged 18 to 70 years old. Participants were broken down into three groups: two comprised of 70 and 76 patients, each treated with Lexapro for seven weeks, and the third group of 48 patients treated with a placebo.

Advertising

“The researchers tested whether brain wave recordings in the first week of treatment would show that the antidepressant (as compared with a placebo) corrected the frequency imbalance – and predict a beneficial effect of medication on an individual’s depression after seven weeks of treatment,” UCLA researchers stated.

Before taking any drugs, all patients received an electroencephalogram and a second one after they completed one full week of treatment or placebo. It was immediately obvious that after only one week of therapy with Lexapro, brain wave recordings began having a distinct pattern compared to patients who took a placebo.

The findings

After reviewing numerous brain wave recordings, Dr. Leuchter became convinced that something important was discovered.

Advertising

“Our biomarker selectively predicted remission with medication, but not placebo. This confirmed that we can differentiate a true, specific response to a drug from a non-specific placebo response. To our knowledge, this is the first time that a biomarker that differentiates placebo remission from drug remission has been reported,” researchers concluded.

Although researchers struck gold by testing Lexapro, more antidepressant drugs are expected to receive new clinical trials, but this time, utilizing brain wave recordings. Researchers hope to improve wait time and save money for patients receiving drug therapy. The testing continues.

10 Fast Facts About Antidepressants

Before taking antidepressants, there are important facts you should know. According to clinical psychologists, if patients would’ve been notified about these deadly risks, the death toll associated with antidepressants would be significantly lower.

Advertising

1. Do NOT take antidepressants if you’ve taken MAOIs (another class of antidepressants). You MUST wait at least 14 days.
2. Antidepressants may increase the risk of suicidal thoughts.
3. Some antidepressant drugs may cause significant weight gain.
4. The full therapeutic benefit of antidepressants can take up to 6 weeks.
5. Do NOT abruptly discontinue antidepressants without advising your doctor.
6. NEVER mix antidepressant drugs with the opioid painkiller Tramadol.
7. Although few antidepressants can treat sexual disorders, others can cause sexual dysfunction.
8. If you have a sudden high fever and see hallucinations, get medical attention right away – you may have Serotonin Syndrome.
9. You should NEVER mix your antidepressant medication with other antidepressants.
10. If one drug does not work for you, don’t stress, there are plenty others to try.

Featured photo credit: Lea Suzuki via sfgate.com

More by this author

Jose Florez

Mental Health Writer

lifestyle-blogs-to-follow-2017 5 Lifestyle Blogs To Follow In 2017 becoming-a-doctor-medical-school How To Become A Doctor In 6 Simple Steps 5-tips-for-a-successful-job-interview 5 Steps To A Successful Job Interview Top 7 Innovative Inventions of 2016 menstruation-7-things-making-period-worse 7 Things Making Your Period Worse

Trending in Brain

1 What Causes Brain Fog? (7 Things You Can Do to Prevent and Stop It) 2 How to Improve Your Brain Memory Naturally: Foods to Eat And Skip 3 7 Natural (And Highly Effective) Ways to Improve Memory 4 15 Ways Meditation Benefits Your Brain Power and Your Mood 5 Do Memory Supplements Work? 10 Supplements to Boost Brain Power

Read Next

Advertising
Advertising

Last Updated on October 29, 2018

What Causes Brain Fog? (7 Things You Can Do to Prevent and Stop It)

What Causes Brain Fog? (7 Things You Can Do to Prevent and Stop It)

Brain fog is more of a symptom than a medical condition itself, but this doesn’t mean it should be ignored. Brain fog is a cognitive dysfunction, which can lead to memory problems, lack of mental clarity and an inability to focus.

Many often excuse brain fog for a bad day, or get so used to it that they ignore it. Unfortunately, when brain fog is ignored it ends up interfering with work and school. The reason many ignore it is because they aren’t fully aware of what causes it and how to deal with it.

It’s important to remember that if your brain doesn’t function fully — nothing else in your life will. Most people have days where they can’t seem to concentrate or forget where they put their keys.

It’s very normal to have days where you can’t think clearly, but if you’re experiencing these things on a daily basis, then you’re probably dealing with brain fog for a specific reason.

So what causes brain fog? It can be caused by a string of things, so we’ve made a list things that causes brain fog and how to prevent it and how to stop it.

1. Stress

It’s no surprise that we’ll find stress at the top of the list. Most people are aware of the dangers of stress. It can increase blood pressure, trigger depression and make us sick as it weakens our immune system.

Another symptom is mental fatigue. When you’re stressed your brain can’t function at its best. It gets harder to think and focus, which makes you stress even more.

Stress can be prevented by following some simple steps. If you’re feeling stressed you should avoid caffeine, alcohol and nicotine — even though it may feel like it helps in the moment. Two other important steps are to indulge in more physical activities and to talk to someone about it.

Advertising

Besides that, you can consider keeping a stress diary, try relaxation techniques like mediation, getting more sleep and maybe a new approach to time management.

2. Diet

Most people know that the right or wrong diet can make them gain or loss weight, but not enough people think about the big impact a specific diet can have on one’s health even if it might be healthy.

One of the most common vitamin deficiencies is vitamin B12 deficiency and especially vegans can be get hid by brain fog, because their diet often lacks the vitamin B-12. The vitamin B12 deficiency can lead to mental and neurological disorders.

The scary thing is that almost 40 % of adults are estimated to lack B12 in their diet. B12 is found in animal products, which is why many vegans are in B12 deficiency, but this doesn’t mean that people need animal products to prevent the B12 deficiency. B12 can be taken as a supplement, which will make the problem go away.

Another vital vitamin that can cause brain fog is vitamin D. More than 1 billion people worldwide don’t have enough vitamin D in their diet. Alongside B12 and vitamin D is omega-3, which because of its fatty acids helps the brain function and concentrate. Luckily, both vitamin D and omega-3 can be taken as supplements.

Then there’s of course also the obvious unhealthy foods like sugar. Refined carbohydrates like sugar will send your blood sugar levels up, and then send you right back down. This will lead to brain fog, because your brain uses glucose as its main source of fuel and once you start playing around with your brain — it gets confused.

Besides being hit by brain fog, you’ll also experience tiredness, mood swings and mental confusion. So, if you want to have clear mind, then stay away from sugar.

Sometimes the same type of diet can be right for some and wrong for others. If you’re experiencing brain fog it’s a good idea to seek out your doctor or a nutritionist. They can take some tests and help you figure out which type of diet works best for your health, or find out if you’re lacking something specific in your diet.

Advertising

3. Allergies

If you have food allergies, or are simply a bit sensitive to specific foods, then eating those foods can lead to brain fog. Look out for dairy, peanuts and aspartame that are known to have a bad effect on the brain.

Most people get their calories from corn, soy and wheat — and big surprise — these foods are some of the most common foods people are allergic to. If you’re in doubt, then you can look up food allergies[1] and find some of the most common symptoms.

If you’re unsure about being allergic or sensitive, then you can start out by cutting out a specific food from your diet for a week or two. If the brain fog disappears, then you’re most likely allergic or sensitive to this food. The symptoms will usually go away after a week or two once you remove the trigger food from the diet.

If you still unsure, then you should seek out the help of your doctor.

4. Lack of sleep

All of us know we need sleep to function, but it’s different for everybody how much sleep they need. A few people can actually function on as little as 3-4 hours of sleep every night, but these people are very, very rare.

Most people need 8 to 9 hours of sleep. If you don’t get the sleep you need, then this will interfere with your brain and you may experience brain fog.

Instead of skipping a few hours of sleep to get ahead of things you need to do, you’ll end up taking away productive hours from your day, because you won’t be able to concentrate and your thoughts will be cloudy.

Many people have trouble sleeping but you can help improve your sleep by a following a few simple steps.

Advertising

There is the 4-7-8 Breathing Exercise, which is a technique that regulates your breath and helps you fall asleep faster. Another well-known technique is to avoid bright lights before you go to sleep.

A lot of us are guilty of falling asleep with the TV on or with our phone right by us, but the blue lights from these screens suppresses the production of melatonin in our bodies, which actually makes us stay awake longer instead. If you’re having trouble going to sleep without doing something before you close your eyes, then try taking up reading instead.

If you want to feel more energized throughout the day, start doing this.

5. Hormonal changes

Brain fog can be triggered by hormonal changes. Whenever your levels of progesterone and estrogen increases, you may experience short-term cognitive impairment and your memory can get bad.

If you’re pregnant or going through menopause, then you shouldn’t worry too much if your mind suddenly starts to get a bit cloudy. Focus on keeping a good diet, getting enough of sleep and the brain fog should pass once you’re back to normal.

6. Medication

If you’re on some medication, then it’s very normal to start experiencing some brain fog.

You may start to forget things that you used to be able to remember, or you get easily confused. Maybe you can’t concentrate the same way that you used to. All of these things can be very scary, but you shouldn’t worry too much about it.

Brain fog is a very normal side effect of drugs, but by lowering your dosage or switching over to another drug; the side effect can’t often be improved and maybe even completely removed.

Advertising

7. Medical condition

Brain fog can often be a symptom of a medical condition. Medical conditions that include inflammation, fatigue, changes in blood glucose level are known to cause brain fog.

Conditions like chronic fatigue syndrome, fibromyalgia, anemia, depression, diabetes, migraines, hypothyroidism, Sjögren syndrome, Alzheimer’s disease, Lupus and dehydration can all cause brain fog.[2]

The bottom line

If you haven’t been diagnosed, then never start browsing around Google for the conditions and the symptoms. Once you start looking for it; it’s very easy to (wrongfully) self-diagnose.

Take a step back, put away the laptop and relax. If you’re worried about being sick, then always check in with your doctor and take it from there.

Remember, the list of things that can cause brain fog is long and it can be something as simple as the wrong diet or not enough sleep.

Featured photo credit: Asdrubal luna via unsplash.com

Reference

[1]Food Allergy: Common Allergens
[2]HealthLine: 6 Possible Causes of Brain Fog

Read Next