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Scientists Find Why Elephants Are Less Likely To Get Cancer

Scientists Find Why Elephants Are Less Likely To Get Cancer
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Did you know that besides humans, animals also die of cancer at the same percentage as us? It is also believed that some animals are moving toward extinction because of this deadly illness. And then, there are those animals that never get cancer. One big example is elephants.

The reason behind why elephants are less likely to get cancer is due to additional copies of a gene encoding tumor protein suppressor, p53. A new study performed by the researchers at Huntsman Cancer Institute at University of Utah Health Sciences, and researchers from the Ringling Bros. Center for Elephant Conservation, shows this phenomenal result. Also, the study conducted that elephants have built-in powerful system of killing cancerous cells.

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Elephants dying out of cancer is 5% compared to 11 to 25% of humans dying out of cancer have baffled the scientists for many years. In order to solve this mystery, the scientists, along with the Ringling Bros. Center for Elephant Conservation, Primary Children’s Hospital, and Utah’s HogleZoo, have performed experiments for several years. On a conclusion, they have discovered that elephants have 38 additional modified copies of a gene that encodes p53, a compound that subdues tumor development. Comparatively, humans have only 2. To come up with a solid answer, the scientists compared the elephants genes with healthy human genes, and genes from a group of patients suffering from Li-Fraumeni Syndrome. The patients have a 90% chance of developing cancer in their lifetime, and have only 1 copy of p53. The lifespan of elephants are from 50 to 70 years, and they have 100 times more cells than us. This made the scientists wonder that among so many cells, at least one or two would trigger cancer. But they don’t.

These results have been published in the Journal of the American Medical Association (JAMA).

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“Nature has already figured out how to prevent cancer. It’s up to us to learn how different animals tackle the problem so we can adapt those strategies to prevent cancer in people,” said co-senior author Joshua Schiffman, M.D., pediatric oncologist at Huntsman Cancer Institute, University of Utah School of Medicine , and Primary Children’s Hospital.

Schiffman and his team scoured through the African elephant genome, and uncovered 40 copies of genes that code for p53. This is a huge amount, given that humans have only 2 copies. What the team did next was they extracted white blood cells from the elephants during their routine check-ups, and subjected the cells to treatments that damage DNA. As a reply, the cells self-destructed, meaning, the cells died, and would be unable to turn into cancer.

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“If you kill the damage cell, it’s gone, and it can’t turn into cancer. This maybe more effective of an approach to cancer prevention than trying to stop a mutated cell from dividing and not being able to completely repair itself,” said Schiffman.

The team, then did another experiment. In order to see if more p53 can prevent cancer, they took cells from elephants (n=8), healthy humans (n=10), and Li-Fraumeni Syndrome patients (n=10), and exposed the cells to radiation. The response showed that elephant cells self-destructed at twice the rate of healthy humans, and more than five times the rate of Li-Fraumeni patients (14.6%, 7.2% and 2.7% respectively). These results supported the idea that more p53 can prevent against cancer. The scientists believe that too much p53 is nature’s way of protecting these majestic animals from cancer.

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Of course, there will be further studies and researches to see if the same can be applied to humans. “If the elephants can hold the key to unlocking some of the mysteries of cancer, then we will see an increased awareness of the plight of elephants worldwide,” said Eric Peterson, elephant manager at Utah’s Hogle Zoo. “What a fantastic benefit: elephants and humans living longer, better lives.”

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Sumaiya Kabir

Sumaiya is a passionate writer who shares thoughts and ideas to help people improve themselves.

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Last Updated on July 12, 2021

100 Incredible Life Hacks That Make Life So Much Easier

100 Incredible Life Hacks That Make Life So Much Easier
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Want to learn some quick and easy life hacks that are easy to do, low cost and saves you time?

By tweaking little things in your daily life, it can make your life much more convenient!

Here’re 100 of the most practical life hacks so you can just pick up any of them right away!

83 tie a small piece of bright colored fabric

    84 write random letter

      85 use a rubberband

        86 dorm smell bad

          87 lean your phone on your sunglassess

            89 how to waterproof your shoes

              90 take a picture of the name card

                91 iron inside out

                  92 old newspaper

                    93 tumble try shoes

                      keep a card like this

                        SONY DSC

                          94 soap bar

                            95 make a hole

                              96 drop the battery

                                97 use a coozie

                                  98 when taking a picture

                                    use a clean dust pan

                                      try a pants hanger

                                        use your cellphone light

                                          use a spring from an old pen

                                            quick and easy iphone speaker

                                              user binder clips

                                                wrap a wet paper towel around your beverage

                                                  put pancake mix in a ketchup bottle

                                                    clean out an old lotion bottle for your beach

                                                      use a muffin tin to serve condiments at a bbq

                                                        doritos are great for kindling

                                                          use nail polish to identify different keys

                                                            use a hanging shoe rack to store cleaning supplies

                                                              freeze grapes to chill white wine without

                                                                use paper clips to organize your cables

                                                                  almost finished your jar of nutella

                                                                    sick of having a box full of tangled

                                                                      unroll the rim to increase the capacity

                                                                        cut open toilet paper rolls and use as a cuff

                                                                          remove the stem from strawberries

                                                                            turn an old bottle into a simple little cord holder

                                                                              for iced coffee and iced cappuccino, use frozen coffee cubes

                                                                                how to fold a fitted bed sheet

                                                                                  tired of snoozing past your alarm

                                                                                    place a rubber band around an open paint can to wipe your brush on

                                                                                      ut a wooden spoon across a boiling pot

                                                                                        use bread clips to save flip-flops

                                                                                          take pictures of friends holding items

                                                                                            how i always know which headphone is the left one

                                                                                              put a stocking over the end of a vacuum

                                                                                                How to make sure you drink enough water

                                                                                                  user a can opener to open blister

                                                                                                    good sandwich guide

                                                                                                      turn your muffin pans upside down

                                                                                                        50 pounds of groceries and living on the 5th floor

                                                                                                          the right way to make a blt

                                                                                                            add one teaspoon of baking soda

                                                                                                              38

                                                                                                                hair straighteners equals to collar irons

                                                                                                                  stack your clothes vertically to see them all

                                                                                                                    the right way to make cookies in the summer

                                                                                                                      how to clean a blender

                                                                                                                        the right way to eat a popsicle

                                                                                                                          use bread clips to label and organize power cords

                                                                                                                            to get the built up residue off of your shower head

                                                                                                                              user a hair clip to orgainize long wires

                                                                                                                                a frozen saturated sponge in a bag

                                                                                                                                  rub stuck zipper teeth with a graphite pencil

                                                                                                                                    use a soda pop tab

                                                                                                                                      50

                                                                                                                                        51 How to multiply large numbers in your head.

                                                                                                                                          52 How to open a bottle if you dont have a corkscrew.

                                                                                                                                            rub a walnut on damaged wooden furniture

                                                                                                                                              kids fall out of bed

                                                                                                                                                use toothpaste to clear up hazy car

                                                                                                                                                  58

                                                                                                                                                    59 keep pizza out while driving home

                                                                                                                                                      60 put your straw through the tab to keep it from rising

                                                                                                                                                        hold oreos with a fork so your fingers

                                                                                                                                                          Never lose your remotes again

                                                                                                                                                            hiding your emergency money

                                                                                                                                                              use a bread tab to hold your spot on a roll

                                                                                                                                                                if you are at a hotel and run out of chargers

                                                                                                                                                                  keep a square of cardboard in a ziplock bag

                                                                                                                                                                    If you need to pee or smoke at a bar

                                                                                                                                                                      drill holes in the bottom of your garbage

                                                                                                                                                                        use an accented letter as your passcode

                                                                                                                                                                          use a squeeze ketchup bottle top with your shopvac

                                                                                                                                                                            do something unusual when locking the door

                                                                                                                                                                              when heating leftovers space out a circle in the middle

                                                                                                                                                                                dont burn yourself in those hard to reach candles

                                                                                                                                                                                  put a small amount of water in a glass when you microwave your pizza

                                                                                                                                                                                    75 use a piece of paper to organize

                                                                                                                                                                                      use half a pool noodle

                                                                                                                                                                                        pencil case to store cables

                                                                                                                                                                                          78 clothespin to hold nail

                                                                                                                                                                                            79 make blts

                                                                                                                                                                                              80 take a picture of your fridge

                                                                                                                                                                                                81 fill plastic water bottles

                                                                                                                                                                                                  82 right ways to eat chips

                                                                                                                                                                                                    99 if your plug keeps failing

                                                                                                                                                                                                      100 put the banana on the wire

                                                                                                                                                                                                        88 before you throw away a post it

                                                                                                                                                                                                          Source: Reddit LifeProTips

                                                                                                                                                                                                          There you go, 100 awesome life hacks that you can try right now to make your life a lot easier!

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