Advertising
Advertising

Scientists Find Why Elephants Are Less Likely To Get Cancer

Scientists Find Why Elephants Are Less Likely To Get Cancer

Did you know that besides humans, animals also die of cancer at the same percentage as us? It is also believed that some animals are moving toward extinction because of this deadly illness. And then, there are those animals that never get cancer. One big example is elephants.

The reason behind why elephants are less likely to get cancer is due to additional copies of a gene encoding tumor protein suppressor, p53. A new study performed by the researchers at Huntsman Cancer Institute at University of Utah Health Sciences, and researchers from the Ringling Bros. Center for Elephant Conservation, shows this phenomenal result. Also, the study conducted that elephants have built-in powerful system of killing cancerous cells.

Advertising

Elephants dying out of cancer is 5% compared to 11 to 25% of humans dying out of cancer have baffled the scientists for many years. In order to solve this mystery, the scientists, along with the Ringling Bros. Center for Elephant Conservation, Primary Children’s Hospital, and Utah’s HogleZoo, have performed experiments for several years. On a conclusion, they have discovered that elephants have 38 additional modified copies of a gene that encodes p53, a compound that subdues tumor development. Comparatively, humans have only 2. To come up with a solid answer, the scientists compared the elephants genes with healthy human genes, and genes from a group of patients suffering from Li-Fraumeni Syndrome. The patients have a 90% chance of developing cancer in their lifetime, and have only 1 copy of p53. The lifespan of elephants are from 50 to 70 years, and they have 100 times more cells than us. This made the scientists wonder that among so many cells, at least one or two would trigger cancer. But they don’t.

These results have been published in the Journal of the American Medical Association (JAMA).

Advertising

“Nature has already figured out how to prevent cancer. It’s up to us to learn how different animals tackle the problem so we can adapt those strategies to prevent cancer in people,” said co-senior author Joshua Schiffman, M.D., pediatric oncologist at Huntsman Cancer Institute, University of Utah School of Medicine , and Primary Children’s Hospital.

Schiffman and his team scoured through the African elephant genome, and uncovered 40 copies of genes that code for p53. This is a huge amount, given that humans have only 2 copies. What the team did next was they extracted white blood cells from the elephants during their routine check-ups, and subjected the cells to treatments that damage DNA. As a reply, the cells self-destructed, meaning, the cells died, and would be unable to turn into cancer.

Advertising

“If you kill the damage cell, it’s gone, and it can’t turn into cancer. This maybe more effective of an approach to cancer prevention than trying to stop a mutated cell from dividing and not being able to completely repair itself,” said Schiffman.

The team, then did another experiment. In order to see if more p53 can prevent cancer, they took cells from elephants (n=8), healthy humans (n=10), and Li-Fraumeni Syndrome patients (n=10), and exposed the cells to radiation. The response showed that elephant cells self-destructed at twice the rate of healthy humans, and more than five times the rate of Li-Fraumeni patients (14.6%, 7.2% and 2.7% respectively). These results supported the idea that more p53 can prevent against cancer. The scientists believe that too much p53 is nature’s way of protecting these majestic animals from cancer.

Advertising

Of course, there will be further studies and researches to see if the same can be applied to humans. “If the elephants can hold the key to unlocking some of the mysteries of cancer, then we will see an increased awareness of the plight of elephants worldwide,” said Eric Peterson, elephant manager at Utah’s Hogle Zoo. “What a fantastic benefit: elephants and humans living longer, better lives.”

More by this author

15 Best Autobiographies Everyone Should Read At Least Once In Their Lives 20 Medical Benefits of Marijuana You Probably Never Knew Science Says People Who Talk To Themselves Are Geniuses Quotes From Socrates That Are Full Of Wisdom 10 Little Things Happy Couples Do Every Day

Trending in Health

1 How to Help Nausea Go Away Fast with These 5 Fixes 2 How to Get out of a Funk and Take Control of Life 3 Study Says Art Makes You Mentally Healthier, Even If You’re Not Good At It 4 How to Get Rid of Refined Sugar Completely 5 How to Stay Calm and Cool When You Are Extremely Stressed

Read Next

Advertising
Advertising
Advertising

Last Updated on June 19, 2019

How to Invest in Yourself: 3 Valuable Ways to Change Your Life

How to Invest in Yourself: 3 Valuable Ways to Change Your Life

Investing in yourself may be the most profitable investment you ever make. It yields not only future returns, but often a current pay-off as well.

The surest way to achieve a better quality life, to be successful, productive, and satisfied is to place a priority on investing in both personal and professional growth. The effort you put into consistently investing in yourself plays a large role in determining the quality of your life now and in the future.

1. Develop Your Skills

Improving your skills doesn’t always mean investing in higher education, though that’s surely an option, and perhaps a necessary one depending upon your career field. Investing in your knowledge and skills can take many forms.

Advertising

In addition, expanding your level of knowledge and skill isn’t limited to the business arena and doesn’t necessarily need to be formal. There are many “skill investment” avenues.

  • Advance your education –  extra classes, advanced degrees, relevant certifications, are all valuable investments. Take classes, either in person or online. (Lifehack also offers this Masterclass that helps you to break free from limitations.)
  • Utilize available training – enroll in workshops, attend conferences or participate in webinars.
  • Expand your knowledge – there’s a lot of information available on nearly any subject imaginable. Read books, articles, white papers, anything related to the talent or skill you want to work on.
  • Keep current – stay abreast of the latest trends or advancements. Subscribe to publications, read blogs of experts, and follow the latest news.

2. Explore Your Creative Side

There is a fountain of creativity within most of us that has never been tapped or certainly hasn’t been used to its highest potential. We may need to unearth, and hone our individual creativity.

Creativity, in any form, helps us to grow personally and professionally, to view problems and solutions in different ways and to utilize other parts of our mind that may have been previously untapped. It’s important to keep in mind that creativity has many faces. It’s far broader than being a painter or sculptor; it’s also about trying new things.

Advertising

  • Learn a new language –  take a class or use language training software.
  • Try gourmet cooking – enroll in a formal class, by a new cookbook, or ask someone you know who enjoys cooking in a different way.
  • Write something – a book, short stories, poetry, anything.
  • Explore the outside world – try gardening, bird watching, or landscape photography.
  • Enjoy music – play an instrument, learn a new one or join a music group of some kind.
  • Create something tangible – paint, sculpt, make pottery, make jewelry or design your own clothes.

Choose some form of activity that you have never tried, haven’t practiced in years, or have never explored fully.

3. Nurture Your Mind and Body

Nurturing both your mind and body allows you to have more to give now and in the future — more energy, more knowledge, more compassion, more ideas, greater strength, physical and mental endurance.

Expand your mind. Learning new things and keeping your mind active even in simple ways helps to grow and maintain your mental ability.

Advertising

  • Read – anything and everything.
  • Explore culture – attend performances, listen to different style of music, travel, or join an organization or group comprised of people from different backgrounds.
  • Open your mind – engage in conversations with those who disagree with you. Look at an argument and try to make a case for the opposing point of view.
  • Keep your mind active – play word games, (yes, even Words with Friends counts,) board games that include strategy, or try using your brain to perform simple calculations rather than relying on a calculator.

Care for your body. Your body is like a well-oiled machine. If you care for it in the way that you might maintain an expensive car, it will perform marvelously and last for a very long time. Remember the basics:

  • Give it high quality fuel – meaning to make healthy food choices as often as possible. What you eat does play a large role in your energy and ability to perform. You truly are what you eat.
  • Don’t push it too hard – meaning to rest and relax often, slow down and don’t overload your system. Also, don’t shift gears too quickly; it causes stress and damage to “your machine,” A.K.A. your body.
  • Get regular and necessary maintenance – meaning to go to the doctor when you’re sick – don’t put it off until you totally break down. Better yet, use preventative maintenance; get check-ups, take appropriate vitamins and pay attention to irregular or erratic behavior.
  • Polish the exterior – meaning to take care of the outside too. Many people dismiss this as frivolous and self-indulgent, but it’s not as long as you don’t go overboard. We’re not talking about facelifts and Botox, we’re talking about getting a fabulous haircut, and wearing clothes that make you feel confident and attractive.

The Bottom Line

Investing in yourself truly makes a difference in your life, your well-being, and your ability to thrive and perform to the best of your ability. The extent to which you invest in yourself, mind and body, not only shapes the way you interact with the outside world, it often reflects the opinion you have of yourself.

Your future is in large part determined by your willingness and ability to invest in yourself now.

Advertising

More About Investing in Yourself

Featured photo credit: Annie Spratt via unsplash.com

Read Next